Johns Hopkins Pilot Study: High-Dose Oral THC Mimics Psilocybin Experience

A Johns Hopkins pilot study found 25mg oral THC can produce altered-state profiles qualitatively similar to 25mg psilocybin when set and setting are controlled. Sample size is only four people, but it's early signal that dose and context push THC into genuinely psychedelic territory — relevant for breeders chasing high-myrcene, sedative cultivars.